abstract：:In an attempt to improve the classification of Bipolar II disorders, we have examined a consecutive series of 687 primary major depressives: 5.1% gave a past history of mania (Bipolar I), 13.7% met our operational criteria for hypomania (Bipolar II), and the remaining 81.2% were provisionally categorized as 'unipolar....

journal_title：Journal of affective disorders

authors： Cassano GB,Akiskal HS,Savino M,Musetti L,Perugi G

更新日期：1992-10-01 00:00:00

abstract：:The recently completed long-term maintenance trial of full-dose imipramine for recurrent unipolar disorder provided an opportunity to examine the extent to which such doses (200-300 mg daily) are associated with persistent and adverse side effects, particularly weight change. In 115 patients we monitored weight change...

journal_title：Journal of affective disorders

authors： Frank E,Kupfer DJ,Buhari A,McEachran AB,Grochocinski VJ

更新日期：1992-09-01 00:00:00

abstract：:Hypofolatemia can cause psychiatric disturbances of a depressive nature. Pregnancy and delivery are often associated with hypofolatemia. This study was conducted to determine if hypofolatemia at day 3 post partum is a risk factor for baby blues or post partum depression. To study this hypothesis, 131 post partum women...

journal_title：Journal of affective disorders

authors： Rouillon F,Thalassinos M,Miller HD,Lemperiere T

更新日期：1992-08-01 00:00:00

abstract：:A possible role for somatostatin in affective disorders is suggested by its low concentration in cerebrospinal fluid of patients with depression. Therefore, we studied the regional effects of antidepressant drugs and antimanic agents on somatostatin concentrations in rat brain. Repeated, but not acute, administration ...

journal_title：Journal of affective disorders

authors： Kakigi T,Maeda K,Kaneda H,Chihara K

更新日期：1992-08-01 00:00:00

abstract：:We explored the differential effect of some climatic factors such as temperature, atmospheric pressure, sunlight duration and humidity grade on the temporal distribution of violent and non-violent suicides, accidental and undetermined causes of death as well as homicides in Belgium, between 1969 and 1984. Our study in...

journal_title：Journal of affective disorders

authors： Linkowski P,Martin F,De Maertelaer V

更新日期：1992-07-01 00:00:00

abstract：:Interpersonal characteristics of the intimate partners of patients with non-melancholic depressive disorders were evaluated as potential predictors of outcome in an eighteen-month, longitudinal study. The short-term reduction in depressive symptoms was predicted most significantly by the patient's perception of the pa...

journal_title：Journal of affective disorders

authors： Hickie I,Parker G

更新日期：1992-06-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) concentrations of immunoreactive corticotropin-releasing hormone (CRH) and somatostatin (SRIF) were measured in female psychiatric inpatients with DSM-III-R diagnoses of major depression, mania, generalized anxiety and somatization disorder. In addition, elderly patients with dementia disorde...

journal_title：Journal of affective disorders

authors： Banki CM,Karmacsi L,Bissette G,Nemeroff CB

更新日期：1992-05-01 00:00:00

abstract：:41 patients who took part in a withdrawal programme from long-term treatment with diazepam in a controlled clinical trial were followed up five years later. Assessments were made of outcome derived from clinical symptomatology, formal psychiatric diagnosis, psychotropic drug use and frequency of contact with both prim...

journal_title：Journal of affective disorders

authors： Holton A,Riley P,Tyrer P

更新日期：1992-04-01 00:00:00

abstract：:The circannual results of the dexamethasone suppression test (DST) were compared in depressed and schizophrenic patients for the periods November-February and March-October. During the winter months, female depressive and schizophrenic patients had lower rates of DST nonsuppression as well as lower concentrations of p...

journal_title：Journal of affective disorders

authors： Rybakowski J,Plocka M

更新日期：1992-02-01 00:00:00

abstract：:Since (a) obsessive-compulsive disorder (OCD) may involve serotonergic neural transmission abnormalities also though to be related to regulation of suicide and aggression, (b) comorbidity between OCD and depression is substantial, and (c) depression is a major risk factor for suicide, a comprehensive analysis of clini...

journal_title：Journal of affective disorders

authors： Beasley CM Jr,Potvin JH,Masica DN,Wheadon DE,Dornseif BE,Genduso LA

更新日期：1992-01-01 00:00:00

abstract：:Saturation binding of the alpha 2-adrenoceptor antagonist, 3H-yohimbine, and displacement of 3H-yohimbine with the alpha 2-adrenoceptor agonist, UK-14,304, were performed concurrently in platelet membranes obtained from drug-free depressed patients and healthy volunteers. Where possible platelet binding was repeated i...

journal_title：Journal of affective disorders

authors： Theodorou AE,Lawrence KM,Healy D,Whitehouse AM,White W,Wilton-Cox H,Kerry SM,Horton RW,Paykel ES

更新日期：1991-11-01 00:00:00

abstract：:Admissions for mania over a 9-year period in New Zealand were analysed, including data from four separate regions spanning nine degrees in latitude. A spring/summer peak of admissions for mania was found. The four regions showed marked, unexpected variability in seasonality. Regression analyses were performed to test ...

journal_title：Journal of affective disorders

authors： Sayer HK,Marshall S,Mellsop GW

更新日期：1991-11-01 00:00:00

abstract：:Thirteen patients with major depressive disorder, 25 patients with dysthymia and 12 healthy controls underwent ergopsychometric testing. The effect of self-paced and set-paced load on mood, vigilance and perseveration tendency was recorded. Within the clinical groups, various types of load seemed to result mainly in v...

journal_title：Journal of affective disorders

authors： Günther V,Kryspin-Exner I

更新日期：1991-10-01 00:00:00

abstract：:Severe depression is characterized by anorexia and weight loss, symptoms that could endanger the patient's nutritional state. In order to investigate the nutritional state of depressed patients we determined the following in 113 healthy controls and depressed inpatients: (1) anthropometric variables such as body weigh...

journal_title：Journal of affective disorders

authors： Maes M,Vandewoude M,Scharpé S,De Clercq L,Stevens W,Lepoutre L,Schotte C

更新日期：1991-09-01 00:00:00

abstract：:Studies of patients' attitudes towards lithium treatment are reviewed. In the present work, a brief questionnaire was developed as a means of identifying and grouping the problems patients commonly have with taking lithium regularly. This 'Lithium Attitudes Questionnaire' was found to yield consistent results which pa...

journal_title：Journal of affective disorders

authors： Harvey NS

更新日期：1991-08-01 00:00:00

abstract：:Rates of depression among panic disorder patients are particularly elevated in patients with comorbid social phobia. However, it is unclear whether this association is specific to social phobia, or whether any comorbid anxiety disorder increases the risk of depression. We assessed 100 panic disorder patients and found...

journal_title：Journal of affective disorders

authors： Reiter SR,Otto MW,Pollack MH,Rosenbaum JF

更新日期：1991-07-01 00:00:00

abstract：:Twenty-nine women were obtained from two community-based facilities and administered the 10-item Edinburgh Postnatal Depression Scale (EDPS) in a computerised and 'pencil and paper' form. A high correlation (r = 0.98) was found between the two test types. The computerised test was found to be acceptable to all women i...

journal_title：Journal of affective disorders

authors： Glaze R,Cox JL

更新日期：1991-05-01 00:00:00

abstract：:This article reports on the treatment received by 38 adolescents during an episode of major depression which had a median duration of 4 months. The one subject who received any pharmacologic treatment was prescribed an antianxiety agent. Sixteen percent received psychotherapy. These results are consistent with evidenc...

journal_title：Journal of affective disorders

authors： Keller MB,Lavori PW,Beardslee WR,Wunder J,Ryan N

更新日期：1991-03-01 00:00:00

abstract：:We evaluated learning and memory in 50 depressed patients prior to and following 4 week treatment with imipramine compared to 21 normal controls tested at corresponding times. At baseline, the depressives did worse than normals on most memory tasks with the difficult memory tasks, regardless of store, modality or type...

journal_title：Journal of affective disorders

authors： Peselow ED,Corwin J,Fieve RR,Rotrosen J,Cooper TB

更新日期：1991-03-01 00:00:00

abstract：:Post-mortem psychiatric diagnoses are compared in two cohorts of male suicides from St. Louis (1956-1957) (Robins, 1981) and San Diego (1981-1982) (Rich et al., 1986). Similar structured interviews and diagnostic criteria had been used in both assessments. Substance/alcohol abuse has remained the major diagnosis in su...

journal_title：Journal of affective disorders

authors： Carlson GA,Rich CL,Grayson P,Fowler RC

更新日期：1991-02-01 00:00:00

abstract：:Differencing and cross-correlations are useful and straightforward methods for dealing with relationships between variables measured over short periods of time. Without such transformations of time-series data, spurious relationships may emerge and the true nature of underlying relationships may be obscured. This rean...

journal_title：Journal of affective disorders

authors： Peck DF

更新日期：1990-12-01 00:00:00

abstract：:Data regarding open-label treatment with fluoxetine following failure to respond to tricyclic antidepressants (TCAs) or intolerance of TCA side effects, suggest a response rate between 51.4% and 62.1%, depending on the definition of TCA refractoriness employed. Double-blind study of this issue would extend these findi...

journal_title：Journal of affective disorders

authors： Beasley CM Jr,Sayler ME,Cunningham GE,Weiss AM,Masica DN

更新日期：1990-11-01 00:00:00

abstract：:The authors conducted a longitudinal study on two samples of patients, fulfilling Research Diagnostic Criteria for schizoaffective disorder and for major affective disorder, respectively. The long-term course in patients defined cross-sectionally as schizoaffective was very heterogeneous. Ten different patterns of cou...

journal_title：Journal of affective disorders

authors： Maj M,Perris C

更新日期：1990-10-01 00:00:00

abstract：:This study investigated the effects of dexamethasone (1 mg orally) on the function of the hypothalamic-pituitary-thyroid (HPT) axis. We determined pre- and post-dexamethasone thyroid-secreting hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), reverse T3 and cortisol levels in 61 depressed inpatients. D...

journal_title：Journal of affective disorders

authors： Maes M,Vandewoude M,Schotte C,Martin M,Blockx P

更新日期：1990-09-01 00:00:00

abstract：:The proportion of patients with a fall-winter pattern of feeling worst comparable to that of patients with seasonal affective disorder (SAD) was 11.4% in our sample of major depressed inpatients. Since admission to psychiatric inpatient services is influenced to an unknown extent by various factors it is not possible ...

journal_title：Journal of affective disorders

authors： Kasper S,Kamo T

更新日期：1990-08-01 00:00:00

abstract：:The advisability of continuing breastfeeding is an important issue for women with postpartum depression or psychosis. A review of the literature on psychotropic drugs in breast milk is presented. All of the major classes of psychotropic drugs (antidepressants, antipsychotics, antianxiety agents, lithium, hypnotics) ha...

journal_title：Journal of affective disorders

authors： Buist A,Norman TR,Dennerstein L

更新日期：1990-07-01 00:00:00

abstract：:To investigate the effect of dexamethasone dosage upon the outcome of the dexamethasone suppression test (DST) and the role of concurrent plasma dexamethasone concentrations, four different dexamethasone dosages were administered to 119 hospitalized depressed patients (0.5 mg: n = 12; 1.0 mg: n = 30; 1.5 mg: n = 42; 2...

journal_title：Journal of affective disorders

authors： Wiedemann K,Holsboer F

更新日期：1990-06-01 00:00:00

abstract：:Tricyclic antidepressants with clinically significant amounts of anticholinergic activity can adversely affect memory and cognitive functioning. The study evaluated the effect of two non-anticholinergic antidepressants, fluoxetine and trazodone, on immediate and short-term memory in clinically depressed outpatients. T...

journal_title：Journal of affective disorders

authors： Fudge JL,Perry PJ,Garvey MJ,Kelly MW

更新日期：1990-04-01 00:00:00

abstract：:We examined the value of the melancholic distinction for predicting response to 1 week of hospitalization without antidepressant drugs and to a 4-week fixed plasma level desipramine (DMI) trial in patients with unipolar non-psychotic major depression. Both DSM-III and III-R criteria were tested. Response to hospitaliz...

journal_title：Journal of affective disorders

authors： Nelson JC,Mazure CM,Jatlow PI

更新日期：1990-03-01 00:00:00

abstract：:Thirty subjects with seasonal affective disorder (SAD) and three subjects with a non-seasonal depression had a trial of phototherapy in an open assessment of the feasibility of phototherapy in clinical practice. 43% of the SAD subjects met the criteria for 'successful treatment', but none of the subjects with non-seas...

journal_title：Journal of affective disorders

authors： Stinson D,Thompson C

更新日期：1990-02-01 00:00:00

abstract：:The pretreatment plasma ratio of tryptophan (Trp) to other large neutral amino acids (LNAA), thought to reflect brain serotonin formation, was determined in 44 inpatients with major depression, who were subsequently treated double-blind on a fixed-dose schedule for 4 weeks with the selective serotonin uptake inhibitor...

journal_title：Journal of affective disorders

authors： Møller SE,Bech P,Bjerrum H,Bøjholm S,Butler B,Folker H,Gram LF,Larsen JK,Lauritzen L,Loldrup D

更新日期：1990-01-01 00:00:00

abstract：:Twenty inpatients suffering from an adjustment disorder with depressed mood according to the DSM-III criteria were compared with 22 inpatients with a (situationally provoked) major depression without an additional DSM-III/axis I diagnosis, with regard to expert- and self-rated symptomatology, social dysfunction and pe...

journal_title：Journal of affective disorders

authors： Bronisch T,Hecht H

更新日期：1989-11-01 00:00:00

abstract：:To investigate the interrelationships between the noradrenergic and serotonergic systems and the hypothalamic-pituitary-adrenal (HPA) axis, we measured the excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) and free cortisol (UFC) in 24-h urine both before and after loading with 2 g L-tryptophan (L-TRP) orally in 24 ...

journal_title：Journal of affective disorders

authors： Maes M,Vandevelde R,Suy E

更新日期：1989-09-01 00:00:00

abstract：:At the present time, there is some concern over the haematological adverse effects of antidepressants. The present paper examines retrospectively 314 clinical trials in depression which were published in English or French between 1958 and 1986 and which used at least one of the following tricyclics: amitriptyline, clo...

journal_title：Journal of affective disorders

authors： Girard M,Biscos-Garreau M

更新日期：1989-09-01 00:00:00

abstract：:In order to evaluate the possible effect of glucocorticoids as neuromodulators of the hypothalamic-pituitary-somatotropic system in depression, cortisol, growth hormone (GH), and insulin-like growth factor I (IGF-I) concentrations were studied before and after oral administration of 1 mg dexamethasone at 11 p.m. in 16...

journal_title：Journal of affective disorders

authors： Rupprecht R,Rupprecht C,Rupprecht M,Noder M,Lesch KP,Mössner J

更新日期：1989-07-01 00:00:00

abstract：:Sulpiride, in this open study of acute manic patients, had a clear antimanic action with all eight patients responding to sulpiride treatment without the need for other antipsychotic drugs. Plasma prolactin concentrations were increased and oestrogen-stimulated neurophysin concentrations decreased by sulpiride but wer...

journal_title：Journal of affective disorders

authors： Christie JE,Whalley LJ,Hunter R,Bennie J,Fink G

更新日期：1989-03-01 00:00:00

abstract：:Thyrotropin secreting hormone (TSH) levels were recorded in baseline conditions and 20 and 60 min after thyrotropin releasing hormone (TRH) administration (200 micrograms i.v.) in 60 depressed females categorized according to DSM-III. Basal TSH (TSHB) and peak TSH responses (TSHP) were measured using ultrasensitive RI...

journal_title：Journal of affective disorders

authors： Maes M,Vandewoude M,Maes L,Schotte C,Cosyns P

更新日期：1989-03-01 00:00:00

abstract：:The density of platelet 3H-imipramine binding sites (Bmax) was investigated in seven inpatients with winter depression before and after incandescent light treatment and in seven healthy volunteers within a 7-day interval without light exposure. A significantly lower mean Bmax value was found in the depressed patients ...

journal_title：Journal of affective disorders

authors： Szádóczky E,Falus A,Arató M,Németh A,Teszéri G,Moussong-Kovács E

更新日期：1989-03-01 00:00:00

abstract：:The lymphocyte stimulation responses to the mitogens phytohemagglutinin (PHA), concanavalin A (Con A) and pokeweed (PWM) were investigated in 30 hospitalized depressed women undergoing a dexamethasone suppression test (DST). Patients were classified according to DSM-III as having major depression with melancholia, wit...

journal_title：Journal of affective disorders

authors： Cosyns P,Maes M,Vandewoude M,Stevens WJ,De Clerck LS,Schotte C

更新日期：1989-01-01 00:00:00

abstract：:This paper examines the effects of parental concordance for affective disorders and psychopathology among the 219 offspring of probands with major depression and normal controls. The lifetime prevalence of psychiatric disorders was significantly higher among the spouses of depressed probands as compared to those of no...

journal_title：Journal of affective disorders

authors： Merikangas KR,Prusoff BA,Weissman MM

更新日期：1988-11-01 00:00:00